Victims of Aggression: Psychological and Biological Consequences
/Organizers:
Manuela Martinez, University of Valencia and Queen Sofia Center for the Study of Violence, Valencia, Spain
Paul F. Brain, University of Wales Swansea, UK
This symposium illustrates that the changes induced by experiencing defeat and/or subordination in male rodents are more detrimental than following more conventional stressors as well as being influenced by genetic factors. Recovery from such experiences is influenced by living conditions and individual differences in stress-responsiveness. Neural activities in the forebrain and brainstem show patterns of adaptation with repeated defeats. Subordination impairs reproduction and causes atherosclerosis in female macaques. A re-evaluation of loss of status as an animal model of anxiety or depression is provided along with details of changes in a variety of receptor systems as well as alterations in neuronal plasticity.
The importance of social housing in social defeat induced changes in behavior and HPA regulation
J.M. Koolhaas, B. Buwalda, M.A.W. Ruis, and S.F. de Boer (University of Groningen, The Netherlands)
The impact of social defeat on cardiac activity in rats
A. Sgoifo, S. F. de Boer, B. Buwalda, F. Maes, and J.M. Koolhaas (University of Groningen, The Netherlands)
Adaptation in patterns of c-fos expression in the brain of male rats by repeated exposure to social defeat
M. Martinez (University of Valencia and The Queen Sofia Center for the Study of Violence, Valencia, Spain)
J. Herbert (University of Cambridge, Cambridge, UK)
F. Martinez-Soriano and A. Calvo-Torrent (University of Valencia, Valencia, Spain)
K.K. Chung (University of Cambridge, Cambridge, UK)
A. A. Valverde, J. L. Paya-Cano and M.A. Pico-Alfonso (University of Valencia, Valencia, Spain)
Development of psychopathological states induced by repeated social defeats in male mice: Strain differences
N. Kudryavtseva (Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia)
Changes in brain serotonergic activity in anxious losers
D. Avgustinovich, D. Lipina, O. Alekseyenko, N. Kudryavtseva (Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia)
Involvement of brain D1 and D2 dopamine receptors in development of depression-like state resulting from repeated social confrontations in male mice
O. Alekseyenko, D. Avgustinovich, and T. Lipina (Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia)
Long-lasting adaptations in opiodergic and aminergic neurons after brief social defeat
E.M. Nikulina, J. E. Marchand, R. M. Kream, and K.A. Miczek (Tufts University, Boston, MA)
Recovery following chronic subordination stress in rats
M.A. Hebert, R. Sakai, C. McKittrick, and R.J. Blanchard (University of Hawaii at Manoa, Honolulu, HI, USA)
The physiologic consequences of subordinate social status in groups of female macaques
J.R. Kaplan (Wake Forest University, Winston-Salem, NC)
S. B. Manuck (University of Pittsburgh, Pittsburgh, PA)
M.R. Adams (Wake Forest University, Winston-Salem, NC)
Further evaluation of loss of status as an animal model of depression
P.F. Brain and L. P. Marrow (University of Wales Swansea, UK)
